PPAR signaling exacerbates mammary gland tumor development
نویسندگان
چکیده
منابع مشابه
PPAR signaling exacerbates mammary gland tumor development
Breast cancer cell lines that express the nuclear peroxisome proliferator-activated receptor (PPAR ) can be prompted to undergo growth arrest and differentiation when treated with synthetic PPAR ligands. To evaluate the therapeutic potential of increased PPAR signaling in vivo, we generated transgenic mice that express a constitutively active form of PPAR in mammary gland. These mice are indist...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2004
ISSN: 0890-9369
DOI: 10.1101/gad.1167804